Table 3.
Selectivity of DC-S303 over other epigenetic targets.
Compound No. | Target | Inhibition Ratio at 100 μM/% |
---|---|---|
DC-S303 | SETD7 | 90.51 |
SETD1B | 27.12 | |
SETD8 | 55.23 | |
G9a | 52.56 | |
SMYD2 | 24.55 | |
EZH2 | 47.88 |
Selectivity of DC-S303 over other epigenetic targets.
Compound No. | Target | Inhibition Ratio at 100 μM/% |
---|---|---|
DC-S303 | SETD7 | 90.51 |
SETD1B | 27.12 | |
SETD8 | 55.23 | |
G9a | 52.56 | |
SMYD2 | 24.55 | |
EZH2 | 47.88 |