Table 3.
Antimicrobial activity of azo-azomethine ligand and its complexes.
| Compound Bacterial Strains |
Inhibition Zone (mm) | MIC and MBC (μg/mL) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligand HL |
Complex 1 |
Complex 2 |
Cam * | DMSO | MIC (MBC) of HL |
MIC (MBC) of complex 1 |
MIC (MBC) of complex 2 |
MIC (MBC) of Cam |
|
|
S. Aureus
(MRSA +ve) |
7 | 13 | 11 | 17 | No zone | 512 (512) |
128 (128) |
256 (256) |
32 (32) |
|
E. Coli
(Gram −ve) |
9 | 15 | 17 | 20 | No zone | 256 (>256) |
64 (256) |
256 (>256) |
32 (128) |
| Fungal strains | Ligand HL | Complex 1 | Complex 2 | Nys * | MIC (MBC) of HL |
MIC (MBC) of complex 1 |
MIC (MBC) of complex 2 |
MIC (MFC) of Nys |
|
| C. Albicans | No zone | No zone | No zone | 22 | No zone | ND | ND | ND | 50 (50) |
| A. Niger | No zone | No zone | No zone | 20 | No zone | ND | ND | ND | 200 (200) |
* Chloramphenicol (Cam) and * Nystatin (Nys) were used as strand drugs for bacteria and fungi, respectively. DMSO was used as a negative control and no effect was detected. ND = Not determined.