Figure 3.
LC-MS/MS chromatograms of plasma and urine before and after injection of (+)-1 into pigs; (a,b) detected (+)-1 (MRM m/z 207.1/110.0), (c,d) detected monohydroxylated metabolites (MRM m/z 223.1/110.0), (e,f) detected monohydroxylated and glucuronidated metabolites (MRM m/z 399.2/223.1). Signals in (c,d) at 5.9 min and (e) at 1.9 min are supposed to result from ion-channel cross talks [26].