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(A,B) SEM, (C) TEM, (D) FL microscopy and (E,F) CLSM micrographs of the uncoated CaCO3 microparticles prepared at room temperature. (B) The SEM micrograph shows the high surface roughness and the porous structure of the microparticles. (D) FL microscopy and (E,F) 3D reconstructed CLSM micrographs were acquired by loading the CaCO3 core microparticles with FITC (green channel). F1 and F2 correspond to the upper (xy) and lateral (xz) views, respectively.
