. 2018 Jan 24;23(2):209. doi: 10.3390/molecules23020209

Table 1.

Chemical structure and IC₅₀ value of flavones.

Flavones	R₁	R₂	R₃	R₄	R₅	R₆	R₇	IC₅₀ *
Flavones	R₁	R₂	R₃	R₄	R₅	R₆	R₇	AGS	AGS-cyr61
Quercetin	OH	OH	H	OH	H	OH	OH	73.1 ± 9.1	46.5 ± 15.1
Tangeretin	H	OCH₃	OCH₃	OCH₃	OCH₃	H	OCH₃	>100	>100
PMF	OCH₃	OCH₃	H	OCH₃	H	OCH₃	OCH₃	49.8 ± 6.4	>200
Nobiletin	H	OCH₃	OCH₃	OCH₃	OCH₃	OCH₃	OCH₃	>100	>100

* IC₅₀: 50% inhibitory concentration. PMF: pentamethoxyflavone.