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. 2018 Apr 4;23(4):830. doi: 10.3390/molecules23040830

Figure 3.

Figure 3

Schematics of aptamer nano-vehicle conjugates. (A) Aptamer-conjugated liposome. NX213 aptamers are directly conjugated with liposomes; (B) An aptamosome. A PSMA aptamer is annealed to linker DNA and conjugated with liposomes to form Dox-encapsulating “aptamosomes”; (C) Aptamer-micelle conjugate. A TDO5 aptamer is conjugated with a PEG-modified lipid to form aptamer-functionalized micelles; (D) Aptamer-nanoparticle conjugate. A Dox-encapsulated PSMA aptamers is conjugated with a quantum dot; (E) Aptamer-polymeric nanoparticle conjugate. An aptamer is conjugated with a PLGA nanoparticle containing docetaxel; (F) Aptamer-DNA origami conjugate. MUC1 aptamers are conjugated with DNA origami harboring gold nanorods and Dox.