Table 2.
Effect of compounds 1 and 3–7 on cultures of LLC-MK2 cells infected and multiplication of T. gondii.
| Cytotoxicity (Infected Culture) a | |||||
|---|---|---|---|---|---|
| Drugs | Concentration (mM) | Uninfected Cells | Infected Cells | Total of Cells | Parasites |
| Control | 0 | 83 ± 8 | 28 ± 4 | 111 ± 12 | 179 ± 29 |
| Compound 1 | 0.18 | 129 ± 6 | 24 ± 4 | 153 ± 10 | 166 ± 15 |
| Control | 0 | 108 ± 19 | 51 ± 6 | 159 ± 25 | 254 ± 38 |
| Compound 3 | 0.077 | 147 ± 3 | 23 ± 5 | 170 ± 8 | 127 ± 32 |
| Control | 0 | 108 ± 19 | 51 ± 6 | 159 ± 25 | 254 ± 38 |
| Compound 4 | 0.038 | 149 ± 24 | 35 ± 10 | 184 ± 34 | 134 ± 32 |
| Control | 0 | 83 ± 8 | 28 ± 4 | 111 ± 12 | 179 ± 29 |
| Compound 5 | 0.16 | 114 ± 3 | 12 ± 1 | 126 ± 4 | 82 ± 19 |
| Control | 0 | 79 ± 7 | 37 ± 3 | 116 ± 10 | 174 ± 16 |
| Compound 6 | 1.33 | 89 ± 12 | 31 ± 5 | 120 ± 17 | 83 ± 23 |
| Control | 0 | 79 ± 7 | 37 ± 3 | 116 ± 10 | 174 ± 16 |
| Compound 7 | 1.46 | 104 ± 9 | 28 ± 3 | 132 ± 12 | 98 ± 12 |
a Values means ± SD.