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. 2018 Mar 3;23(3):574. doi: 10.3390/molecules23030574

Table 1.

NCI IC50 data after five-dose testing: DMSO solution of compound (100 µL) was added to plates, which were incubated for 48 h at 37 °C using 5% CO2 (humidified atmosphere). Sulforhodamine B (SRB) assay was used to evaluate cytotoxicity.

Compound IC50 DU-145 (µM) IC50 MCF-7 (µM)
1 3.388 0.295
4a 27.542 3.388
4b 5.248 1.348