Table 4.
Kyoto Encyclopedia of Genes and Genomes (KEGG) annotation of differentially expressed genes (DEG) belonging to cluster 9 (genes up-regulated in the untreated celiac disease patient: CC8).
| KEGG ID | Description | p |
|---|---|---|
| 04512 | Extra-cellular matrix-receptor interaction | 8.06 × 10−10 |
| 04640 | Hematopoietic cell lineage | 8.37 × 10−9 |
| 00643 | Styrene degradation | 8.74 × 10−7 |
| 00590 | Prostaglandin and leukotriene metabolism | 8.19 × 10−6 |
| 04510 | Focal adhesion | 3.35 × 10−5 |
| 04610 | Complement and coagulation cascade | 0.000131 |
| 04810 | Regulation of actin cytoskeleton | 0.000529 |
| 04330 | Notch signaling | 0.00128 |
| 04540 | Gap junction | 0.00951 |
| 00350 | Tyrosine metabolism | 0.011 |
| 00230 | Purine metabolism | 0.019 |
| 04020 | Calcium signaling pathway | 0.0193 |
| 04060 | Cytokine-cytokine receptor interaction | 0.0262 |
| 00564 | Glycerophospholipid metabolism | 0.0267 |
Only KEGG pathways that result significantly regulated (p-value < 0.05 against the null hypothesis that their enrichment in DEG is random) are given in the Table.