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. 2018 Jun 19;8:193. doi: 10.3389/fcimb.2018.00193

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Copyright © 2018 Santos, Adhikarla, Yan, Wang, Fouts, Vinetz, Alcantara, Hartskeerl, Goris, Picardeau, Reis, Townsend, Zhao, Ko and Wunder.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phylogenetic relationship among Leptospira interrogans serovar Copenhageni and Icterohaemorrhagiae strains. Maximum likelihood tree depicting phylogenetic relationship among Leptospira interrogans serovars Copenhageni and Icterohaemorrhagiae from different geographical locations. Phylogeny constructed using the SNPs sites. Asterisk (^*) represents clusters with statistical Bootstrap support higher than 70%. The sequences from serovar Icterohaemorrhagiae are underlined. L. interrogans serovar Lai was used as an outgroup for this analysis. The strain sequences are colored by country of isolation following the legend. The clusters numbers are related to country of isolation: 1A−1F (Brazil), 2 (Hawaii, US), 3 (French Polynesia), 4 (Egypt, Netherlands and Denmark), 5 (Japan), 6 (Guadalupe and Slovenia), and 7 (Colombia).