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. 2018 Jun 25;8:9670. doi: 10.1038/s41598-018-27800-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Synteny analysis of the genomes and its reference. For each letter, the top side of the figure represents the genomes before using Pan4Draft and the bottom side represents the genomes after using Pan4Draft. The X axe represents the reference and the Y axe represents the ordered multifasta file. (a) the synteny analysis of E. coli P12b (SRA SRX1012260, Run SRR2000272. (b) synteny analysis of E. coli K-12 str. GM4792 Lac+ (SRA SRX1295865, RUN SRR2537294). (c) E. coli RR1 (SRA SRX1021885, RUN SRR2014554). (d) E. coli KLY (SRA SRX610250, RUN SRR1424625). (e) E. coli 042 (SRA ERX002221, RUN ERR007646). (f) E. coli 042 (SRA ERX002221, RUN ERR007646).