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. 2018 Jun 25;8:9670. doi: 10.1038/s41598-018-27800-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Orthologs cluster analysis of the pan-genome shows that the clusters are more similar between the complete genome and the genome after using Pan4Draft. (a) represents the orthologs cluster of the complete genomes (b) represents the orthologs cluster of the genome before using Pan4Draft and (c) represents the orthologs cluster after using Pan4Draft.