Fig. 6. Multiple axial CT images in arterial phase in a 71 year-old man with HCC who was treated by DEB-TACE that demonstrate the most commonly employed radiologic response criteria.

(A) product of the bidimensional measurements of the HCC on CT prior to DEB-TACE is 4.2 cm × 2.7 cm = 11.34. (B) product of the bidimensional measurements of the HCC on CT 1 month after DEB-TACE is 2.7 cm × 2.6 cm = 7.02. This lesion is thus classified as stable disease by WHO criteria because it did not achieve a >50% reduction in size. (C) per RECIST criteria, the longest unidimensional measurement of the HCC on CT prior to TACE is recorded (4.2 cm). (D) on follow-up imaging, the longest unidimensional measurement is 2.7 cm, a >30% decrease in size. This is a partial response by RECIST criteria. (E) product of the bidimensional measurement of the enhancing portion of the HCC on CT prior to DEB-TACE is 4.2 cm × 2.7 cm = 11.34. (F) follow-up imaging demonstrates no residual arterial, a complete response by EASL criteria. (G) per mRECIST criteria, the longest unidimensional measurement of the enhancing portion of the HCC on CT prior to TACE is recorded (4.2 cm). (H) follow-up imaging demonstrates no residual arterial enhancement, a complete response by mRECIST criteria.