TABLE 1.
Diagnostic sensitivity and specificity for all tests and sample types compared with culture as the reference standarda
| Specimen type (n) | Test (n) | % Sensitivity (95% CI) | % Specificity (95% CI) |
|---|---|---|---|
| Turbid blood culture with GNB (252) | AMD (252) | 99.0 (94.6–100) | 100 (97.6–100) |
| Latex (237) | 99.0 (94.5–100) | 100 (97.4–100) | |
| IFA (176) | 100 (94.8–100) | 98.1 (93.4–99.8) | |
| P value | NS* | NS** | |
| Pus (139) | AMD (139) | 47.1 (23.0–72.2) | 100 (97.0–100) |
| IFA (95) | 66.7 (29.9–92.5) | 90.7 (82.5–95.9) | |
| P value | 0.338 | 0.0006 | |
| Sputum (23) | AMD (23) | 33.3 (0.84–90.6) | 100 (83.2–100) |
| IFA (23) | 100 (29.2–100) | 85.0 (62.1–96.8) | |
| P value | 0.083 | 0.072 | |
| Sterile fluid (46) | AMD (46) | 0 (0–84.2) | 100 (92.0–100) |
| IFA (43) | 100 (15.8–100) | 100 (91.4–100) | |
| P value | 0.046 | 1.0 | |
| Urine selected (241) | AMD (241) | 86.7 (59.5–98.3) | 90.7 (86.2–94.2) |
a
NS, not significant; CI, confidence interval; n, number of samples. *, P = 0.994 for AMD versus latex, 0.402 for latex versus IFA, 0.405 for IFA versus AMD; **, P = 1.0 for AMD versus latex, 0.107 for latex versus IFA, 0.169 for IFA versus AMD.