TABLE 2.
Clinical backgrounds of children with invasive nontypeable Haemophilus influenzae diseases in Japan
| Strain no. | Yr of isolation | Patient age | Prefecture | Underlying disease(s)a | Hib vaccination (no. of doses)b | Clinical diagnosis | Disease outcome |
|---|---|---|---|---|---|---|---|
| 1 | 2008 | 1 yr | Kagoshima | None | 0 | Bacteremia | No complications |
| 2 | 2008 | 10 yr | Kochi | Reye's syndrome | 0 | Pneumonia | No complications |
| 3 | 2010 | 0 mo | Chiba | None | 0 | Pneumonia | No complications |
| 4 | 2010 | 2 yr | Fukuoka | Seckel syndrome | 0 | Bacteremia | Died |
| 5 | 2010 | 0 mo | Fukuoka | Preterm, LBW | 0 | Bacteremia | No complications |
| 6 | 2010 | 14 yr | Chiba | None | 0 | Bacteremia | No complications |
| 7 | 2010 | 1 yr | Chiba | None | 0 | CPAOA | Died |
| 8 | 2010 | 4 yr | Fukuoka | None | 0 | Bacteremia | No complications |
| 9 | 2011 | 1 mo | Chiba | None | 0 | Bacteremia | No complications |
| 10 | 2011 | 5 yr | Kagoshima | Acute lymphocytic leukemia | 0 | Bacteremia | No complications |
| 11 | 2011 | 1 yr | Chiba | None | 1 | Pneumonia | No complications |
| 12 | 2012 | 1 yr | Nagasaki | Long QT syndrome | 3 | Bacteremia | Died |
| 13 | 2012 | 7 mo | Fukuoka | Infant hepatitis, PA | 2 | Pneumonia | No complications |
| 14 | 2012 | 4 yr | Fukuoka | PA, VSD, major aortopulmonary collateral artery | 1 | Pneumonia | No complications |
| 15 | 2012 | 1 yr | Kagoshima | None | 1 | Meningitis | No complications |
| 16 | 2012 | 7 mo | Fukuoka | None | 3 | Pneumonia | No complications |
| 17 | 2012 | 2 yr | Chiba | None | 0 | Sinusitis | No complications |
| 18 | 2012 | 8 mo | Fukuoka | None | 0 | Bacteremia | No complications |
| 19 | 2012 | 10 yr | Chiba | None | 0 | Sinusitis | No complications |
| 20 | 2012 | 1 yr | Okinawa | None | 1 | Bacteremia | No complications |
| 21 | 2012 | 1 yr | Okinawa | None | 4 | Bacteremia | No complications |
| 22 | 2013 | 8 yr | Chiba | Chromosomal abnormality, hydrocephalus | 1 | Peritonitis | No complications |
| 23 | 2013 | 0 mo | Tokyo | Extremely LBW | 0 | Bacteremia | No complications |
| 24 | 2013 | 11 mo | Tokyo | None | 3 | Bacteremia | No complications |
| 25 | 2014 | 1 yr | Shizuoka | None | 4 | Pneumonia | No complications |
| 26 | 2014 | 4 yr | Chiba | None | 1 | Pneumonia | No complications |
| 27 | 2015 | 3 yr | Chiba | Preterm, LBW, jawless, tracheotomy | 4 | Pneumonia | No complications |
| 28 | 2015 | 11 mo | Chiba | None | 3 | Pneumonia | No complications |
a
LBW, low birth weight; PA, pulmonary atresia; VSD, ventricular septal defect; CPAOA, cardiac pulmonary arrest on arrival.
b
Number of doses received.