TABLE 1.
Variable class and name | Categoryb | Nc | % toxin positive | Relative risk | P valued |
---|---|---|---|---|---|
History | |||||
Prior CDIa | Previous CDI | 51 | 63 | 1.5 | .015 |
No previous CDI | 109 | 42 | |||
IBD | Diagnosis of IBD | 20 | 35 | 0.7 | .207 |
No diagnosis of IBD | 132 | 50 | |||
Immunocompromised | Immunocompromised | 44 | 50 | 1.0 | .760 |
Not immunocompromised | 110 | 47 | |||
Symptoms | |||||
Fever | Temp ≥38°C | 51 | 59 | 1.4 | .077 |
Temp <38°C | 90 | 43 | |||
Duration of diarrhea | ≥2 Days | 139 | 50 | 1.6 | .142 |
<2 Days | 16 | 31 | |||
Stool frequency | ≥3 Loose stools per day | 135 | 50 | 1.5 | .142 |
<3 Loose stools per day | 21 | 33 | |||
Treatment | |||||
Laxative | Laxative use within 24 h of stool collection | 23 | 43 | 0.9 | .632 |
No laxative within 24 h of stool collection | 133 | 49 | |||
Recent antibiotic | Antibiotic use in the prior 2 weeks | 104 | 52 | 1.1 | .472 |
No antibiotic use in the prior 2 weeks | 44 | 45 | |||
Recent cephalosporin | Cephalosporin use in the prior 2 weeks | 35 | 57 | 1.3 | .215 |
No cephalosporin use in the prior 2 weeks | 85 | 45 | |||
Recent quinolone | Quinolone use in the prior 2 weeks | 15 | 60 | 1.3 | .333 |
No quinolone use in the prior 2 weeks | 105 | 47 | |||
Enteral nutrition | Tube feeding within 24 h of stool collection | 8 | 38 | 0.8 | .537 |
No tube feeding within 24 h of stool collection | 146 | 49 |
Prior C. difficile infection was defined as having a positive PCR result at any point in the past, with the majority of patients with recurrent CDI having a prior CDI within the last year.
IBD, Inflammatory bowel disease.
N, number of patients.
Values in boldface are significant.