Table 3.

Secondary metabolite biosynthetic gene clusters (BGC) identified in the genome of Streptomyces sp. NP10 and their presence in the genomes of closely related species S. griseus XyelbKG-1 and Streptomyces sp. JS01 using antiSMASH 4.0 software followed by manual curation.

NP10 BGC No.	NP10 BGC type	Putative product	XyelbKG-1	JS01
2	Terpene	Terpenoid	+	+
8	Lantipeptide	AfmS-like class III lantipeptide	+	+
9	PKS I-NRPS	polyketide-NR peptide hybrid	+	+
12-1	Butyrolactone	γ-butyrolactone	+	+
12-2	Fatty acid	fatty acids	-	+
15	Lantipeptide	class II lantipeptides	+	+
16	Lasso peptide	Lasso peptide, class II	+	+
17	Ectoine-butyrolactone	unknown	-	-
18	Ectoine	ectoine	+	+
23	Fatty acid	fatty acids	+	+
27	Siderophore	desferrioxamine B	+	+
30	Siderophore	siderophore	+	+
34	Bacteriocin	bacteriocin	+	+
37	Fatty acid	fatty acids	+	+
42	PKS I-NRPS	polyketide-NR peptide hybrid	+	+
43	PKS III	alkylresorcinol	+	+
44	Melanin	melanin	+	+
45	Terpene	2-methyl isoborneol	+	+
46-1	Bacteriocin	linocin M18-like bacteriocin	+	+
46-2	PKS I-NRPS	polycyclic tetramate macrolactam	+	+
49	Terpene	lycopene-like terpenoid, glycosylated	-	-
55	PKS I-NRPS	diketopiperazines	-	+
56	NRPS	non-ribosomal peptide	-	-
61	Terpene	terpenoid	+	+
64	Fatty acid	fatty acids	+	+
68	Terpene	hopanoids	+	+
70-1	PKS III	1,3,6,8-tetrahydroxynaphthalene	+	+
70-2	Fatty acid	fatty acids	+	+
71	Terpene	isorenieratene	+	+
72	NRPS	griseobactin	+	+
73	PKS II-PKS I	polyketide, glycosylated	-	+
76	Terpene	geosmin	+	+
77	Butyrolactone	γ-butyrolactone	+	+
80	Terpene	terpenoid	-	-

Gene cluster that has been subject to this study is in bold.