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DTI directionally encoded color maps in the coronal plane at P90 demonstrate loss of microstructure in vehicle-treated CCI rats that is not present in EPO-treated CCI rats. White arrows highlight the loss of microstructure and diffusion abnormalities in CCI-veh rats compared to shams, and partial improvement with EPO treatment. Impaired diffusion and loss of microstructure causes loss of directional coherence. (Red–transverse, green–vertical, and blue–orthogonal to the plane).
