Table 4.
Abundance of genus-level taxa (percent of total sequences) in the fecal microbiota of domestic cats (Felis catus) fed either kibbled (n = 9) or canned (n = 9) diet at 8, 17, 104, and 260 weeks of age.
| Kibbled | Canned | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 8 weeks of age | 17 weeks of age | 104 weeks of age | 260 weeks of age | 8 weeks of age | 17 weeks of age | 104 weeks of age | 260 weeks of age | P-value | FDR | |||||||||||||||
| Phylum | Family | Genus | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Diet | Week | Diet × Week | Diet | Week | Diet × Week |
| Actinobacteria | ||||||||||||||||||||||||
| Bifidobacteriaceae | Bifidobacterium | 2.950 | 0.676 | 4.522 | 1.351 | 0.166 | 0.135 | 0.175 | 0.082 | 0.001 | 0.000 | 0.001 | 0.001 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |
| Coriobacteriaceae | Asaccharobacter | 0.078 | 0.026 | 0.184 | 0.045 | 0.284 | 0.047 | 0.144 | 0.027 | 0.084 | 0.034 | 0.024 | 0.012 | 0.015 | 0.003 | 0.091 | 0.017 | 0.000 | 0.135 | 0.000 | 0.000 | 0.190 | 0.000 | |
| Collinsella | 0.727 | 0.159 | 1.144 | 0.156 | 0.202 | 0.060 | 0.297 | 0.103 | 0.092 | 0.035 | 0.066 | 0.021 | 0.017 | 0.006 | 0.042 | 0.009 | 0.000 | 0.000 | 0.002 | 0.000 | 0.000 | 0.008 | ||
| Bacteroidetes | ||||||||||||||||||||||||
| Bacteroidaceae | Bacteroides | 2.963 | 1.170 | 0.078 | 0.033 | 3.170 | 0.978 | 1.107 | 0.219 | 9.664 | 1.479 | 1.841 | 0.712 | 12.505 | 3.229 | 5.367 | 1.887 | 0.000 | 0.000 | 0.119 | 0.000 | 0.000 | 0.248 | |
| Uncl. Bacteroidales | Uncl. Bacteroidales | 0.015 | 0.007 | 0.001 | 0.001 | 0.059 | 0.018 | 0.022 | 0.005 | 0.122 | 0.029 | 0.119 | 0.034 | 0.191 | 0.022 | 0.098 | 0.020 | 0.000 | 0.002 | 0.555 | 0.000 | 0.005 | 0.650 | |
| Porphyromonadaceae | Uncl. Porphyromonadaceae | 0.062 | 0.039 | 0.010 | 0.010 | 0.089 | 0.025 | 0.042 | 0.012 | 0.222 | 0.085 | 0.050 | 0.018 | 0.063 | 0.014 | 0.175 | 0.050 | 0.006 | 0.039 | 0.177 | 0.011 | 0.067 | 0.328 | |
| Parabacteroides | 0.284 | 0.157 | 0.004 | 0.004 | 0.139 | 0.039 | 0.011 | 0.003 | 0.173 | 0.051 | 0.040 | 0.024 | 0.038 | 0.011 | 0.038 | 0.018 | 0.458 | 0.002 | 0.723 | 0.573 | 0.005 | 0.785 | ||
| Prevotellaceae | Uncl. Prevotellaceae | 0.769 | 0.308 | 0.150 | 0.087 | 2.126 | 0.839 | 1.858 | 0.384 | 7.932 | 0.991 | 6.096 | 1.413 | 7.948 | 1.734 | 10.274 | 1.450 | 0.000 | 0.047 | 0.555 | 0.000 | 0.076 | 0.650 | |
| Prevotella | 12.856 | 2.192 | 7.791 | 3.147 | 21.344 | 2.878 | 38.136 | 4.368 | 11.917 | 2.347 | 6.815 | 1.632 | 8.532 | 1.903 | 16.021 | 3.390 | 0.000 | 0.000 | 0.001 | 0.000 | 0.000 | 0.003 | ||
| Firmicutes | ||||||||||||||||||||||||
| Enterococcaceae | Enterococcus | 2.433 | 2.086 | 2.772 | 1.793 | 0.010 | 0.010 | 0.006 | 0.005 | 0.350 | 0.296 | 0.283 | 0.165 | 0.005 | 0.002 | 0.081 | 0.055 | 0.533 | 0.167 | 0.584 | 0.629 | 0.220 | 0.663 | |
| Lactobacillaceae | Lactobacillus | 6.849 | 1.828 | 10.826 | 2.364 | 0.000 | 0.000 | 0.043 | 0.025 | 0.002 | 0.002 | 0.002 | 0.001 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |
| Streptococcaceae | Lactococcus | 1.188 | 0.508 | 0.000 | 0.000 | 0.000 | 0.000 | 0.007 | 0.007 | 0.014 | 0.006 | 0.021 | 0.014 | 0.000 | 0.000 | 0.000 | 0.000 | 0.010 | 0.000 | 0.000 | 0.017 | 0.000 | 0.000 | |
| Streptococcus | 5.164 | 3.222 | 2.686 | 2.563 | 1.117 | 1.109 | 0.016 | 0.013 | 0.004 | 0.002 | 0.071 | 0.062 | 0.001 | 0.000 | 0.001 | 0.001 | 0.026 | 0.387 | 0.249 | 0.040 | 0.440 | 0.402 | ||
| Clostridiaceae | Clostridium | 0.737 | 0.616 | 0.103 | 0.063 | 0.187 | 0.107 | 0.802 | 0.393 | 4.167 | 1.796 | 10.033 | 4.073 | 1.994 | 0.655 | 3.159 | 1.200 | 0.000 | 0.049 | 0.029 | 0.000 | 0.077 | 0.075 | |
| Eubacteriaceae | Eubacterium | 0.499 | 0.320 | 0.827 | 0.112 | 1.234 | 0.359 | 0.432 | 0.133 | 1.392 | 0.318 | 2.094 | 0.426 | 2.516 | 0.248 | 2.874 | 0.355 | 0.000 | 0.014 | 0.053 | 0.000 | 0.026 | 0.121 | |
| Clostridiales Incertae Sedis XIV | Blautia | 10.263 | 4.093 | 13.056 | 2.895 | 6.465 | 0.824 | 8.708 | 0.935 | 3.640 | 0.881 | 5.288 | 0.958 | 6.094 | 0.963 | 7.790 | 1.823 | 0.000 | 0.444 | 0.130 | 0.001 | 0.493 | 0.261 | |
| Lachnospiraceae | Coprococcus | 2.337 | 0.381 | 2.565 | 0.577 | 3.196 | 0.430 | 2.058 | 0.266 | 1.667 | 0.443 | 2.671 | 0.305 | 2.511 | 0.251 | 2.528 | 0.346 | 0.667 | 0.138 | 0.275 | 0.730 | 0.190 | 0.405 | |
| Uncl. Lachnospiraceae | 3.529 | 1.549 | 3.199 | 1.183 | 2.996 | 0.520 | 2.694 | 0.384 | 2.478 | 0.401 | 2.073 | 0.362 | 3.370 | 0.427 | 2.877 | 0.403 | 0.392 | 1.000 | 0.521 | 0.503 | 1.000 | 0.650 | ||
| Roseburia | 0.022 | 0.016 | 0.000 | 0.000 | 0.154 | 0.048 | 0.230 | 0.081 | 0.087 | 0.048 | 0.005 | 0.002 | 0.254 | 0.107 | 0.167 | 0.088 | 0.563 | 0.001 | 0.396 | 0.639 | 0.003 | 0.535 | ||
| Uncl. Clostridiales | Uncl. Clostridiales | 2.626 | 0.400 | 2.474 | 0.540 | 4.814 | 0.865 | 2.431 | 1.201 | 2.495 | 0.504 | 5.306 | 0.963 | 4.146 | 0.582 | 4.678 | 0.443 | 0.039 | 0.060 | 0.046 | 0.056 | 0.091 | 0.110 | |
| Peptococcaceae | Peptococcus | 0.375 | 0.106 | 0.947 | 0.447 | 0.365 | 0.058 | 0.136 | 0.023 | 0.610 | 0.144 | 1.124 | 0.336 | 0.802 | 0.140 | 1.016 | 0.183 | 0.001 | 0.040 | 0.307 | 0.002 | 0.067 | 0.439 | |
| Peptostreptococcaceae | Uncl. Peptostreptococcaceae | 17.905 | 3.213 | 27.179 | 2.932 | 14.866 | 1.648 | 8.101 | 1.152 | 16.008 | 2.719 | 33.242 | 3.810 | 29.994 | 4.350 | 23.425 | 3.924 | 0.000 | 0.000 | 0.014 | 0.000 | 0.000 | 0.039 | |
| Peptostreptococcus | 0.103 | 0.085 | 0.010 | 0.003 | 0.006 | 0.003 | 0.005 | 0.002 | 0.962 | 0.643 | 0.811 | 0.388 | 0.025 | 0.010 | 0.025 | 0.009 | 0.006 | 0.040 | 0.107 | 0.011 | 0.067 | 0.232 | ||
| Sporacetigenium | 0.024 | 0.010 | 0.057 | 0.019 | 0.573 | 0.149 | 0.271 | 0.167 | 0.023 | 0.008 | 0.307 | 0.189 | 0.389 | 0.181 | 0.176 | 0.144 | 1.000 | 0.004 | 0.482 | 1.000 | 0.008 | 0.618 | ||
| Ruminococcaceae | Acetanaerobacterium | 0.139 | 0.047 | 0.161 | 0.064 | 0.326 | 0.038 | 0.091 | 0.013 | 0.540 | 0.288 | 0.488 | 0.149 | 0.507 | 0.163 | 0.738 | 0.083 | 0.000 | 0.796 | 0.391 | 0.000 | 0.829 | 0.535 | |
| Butyricicoccus | 0.088 | 0.032 | 0.025 | 0.011 | 0.164 | 0.037 | 0.121 | 0.023 | 0.287 | 0.086 | 0.203 | 0.066 | 0.144 | 0.023 | 0.158 | 0.028 | 0.000 | 0.332 | 0.039 | 0.000 | 0.386 | 0.097 | ||
| Faecalibacterium | 0.138 | 0.057 | 0.219 | 0.107 | 0.673 | 0.148 | 2.224 | 0.251 | 0.298 | 0.135 | 0.372 | 0.129 | 0.743 | 0.079 | 0.822 | 0.102 | 0.018 | 0.000 | 0.000 | 0.029 | 0.000 | 0.000 | ||
| Oscillibacter | 0.033 | 0.024 | 0.004 | 0.002 | 0.351 | 0.071 | 0.112 | 0.030 | 0.050 | 0.023 | 0.016 | 0.009 | 0.152 | 0.041 | 0.103 | 0.027 | 0.064 | 0.000 | 0.003 | 0.088 | 0.000 | 0.010 | ||
| Uncl. Ruminococcaceae | 0.638 | 0.289 | 0.192 | 0.101 | 2.204 | 0.433 | 0.505 | 0.096 | 2.817 | 0.937 | 1.696 | 0.431 | 3.020 | 0.358 | 2.568 | 0.253 | 0.000 | 0.006 | 0.425 | 0.000 | 0.012 | 0.559 | ||
| Ruminococcus | 0.000 | 0.000 | 0.006 | 0.006 | 1.227 | 0.237 | 0.150 | 0.080 | 0.003 | 0.002 | 0.000 | 0.000 | 0.004 | 0.004 | 0.002 | 0.002 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | ||
| Subdoligranulum | 0.022 | 0.018 | 0.106 | 0.032 | 0.782 | 0.307 | 0.482 | 0.125 | 0.007 | 0.006 | 0.001 | 0.001 | 0.002 | 0.001 | 0.002 | 0.002 | 0.000 | 0.002 | 0.002 | 0.000 | 0.005 | 0.008 | ||
| Veillonellaceae | Acidaminococcus | 1.188 | 0.733 | 0.330 | 0.263 | 0.063 | 0.044 | 0.234 | 0.126 | 0.004 | 0.002 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | 0.065 | 0.255 | 0.205 | 0.088 | 0.304 | 0.342 | |
| Allisonella | 0.202 | 0.051 | 0.054 | 0.019 | 0.064 | 0.011 | 0.071 | 0.017 | 0.174 | 0.037 | 0.374 | 0.092 | 0.039 | 0.007 | 0.084 | 0.018 | 0.013 | 0.000 | 0.000 | 0.022 | 0.000 | 0.000 | ||
| Megamonas | 1.672 | 0.664 | 2.058 | 1.760 | 0.685 | 0.306 | 1.933 | 0.624 | 3.517 | 1.346 | 1.712 | 0.710 | 1.031 | 0.331 | 0.608 | 0.113 | 0.521 | 0.182 | 0.273 | 0.629 | 0.233 | 0.405 | ||
| Megasphaera | 10.199 | 5.284 | 10.947 | 4.906 | 11.910 | 2.905 | 14.285 | 3.222 | 0.480 | 0.234 | 0.014 | 0.009 | 0.001 | 0.000 | 0.167 | 0.150 | 0.000 | 0.875 | 1.000 | 0.000 | 0.893 | 1.000 | ||
| Uncl. Veillonellaceae | 0.104 | 0.024 | 0.020 | 0.009 | 0.199 | 0.030 | 0.186 | 0.019 | 0.181 | 0.034 | 0.059 | 0.022 | 0.107 | 0.030 | 0.102 | 0.021 | 1.000 | 0.000 | 0.000 | 1.000 | 0.000 | 0.000 | ||
| Phascolarctobacterium | 1.968 | 0.470 | 0.164 | 0.103 | 4.067 | 0.421 | 6.611 | 0.479 | 4.284 | 0.553 | 1.442 | 0.641 | 3.242 | 0.217 | 4.547 | 0.861 | 0.863 | 0.000 | 0.000 | 0.899 | 0.000 | 0.000 | ||
| Erysipelotrichaceae | Uncl. Erysipelotrichaceae | 1.428 | 0.372 | 2.259 | 0.418 | 1.375 | 0.204 | 0.564 | 0.147 | 1.196 | 0.387 | 1.195 | 0.332 | 0.260 | 0.073 | 0.198 | 0.085 | 0.001 | 0.000 | 0.261 | 0.001 | 0.000 | 0.405 | |
| Turicibacter | 0.001 | 0.001 | 0.042 | 0.042 | 0.552 | 0.398 | 0.128 | 0.104 | 0.000 | 0.000 | 0.000 | 0.000 | 0.015 | 0.010 | 0.005 | 0.004 | 0.039 | 0.105 | 0.189 | 0.056 | 0.154 | 0.338 | ||
| Fusobacteria | ||||||||||||||||||||||||
| Fusobacteriaceae | Cetobacterium | 0.002 | 0.002 | 0.000 | 0.000 | 0.007 | 0.004 | 0.009 | 0.008 | 0.728 | 0.717 | 1.264 | 1.024 | 0.011 | 0.006 | 0.006 | 0.006 | 0.009 | 0.228 | 0.559 | 0.015 | 0.278 | 0.650 | |
| Fusobacterium | 0.857 | 0.459 | 0.126 | 0.063 | 0.262 | 0.169 | 0.194 | 0.080 | 11.495 | 2.651 | 8.440 | 1.950 | 3.282 | 0.941 | 3.716 | 1.438 | 0.000 | 0.002 | 0.005 | 0.000 | 0.005 | 0.016 | ||
| Uncl. Fusobacteriaceae | 0.985 | 0.829 | 0.049 | 0.041 | 0.869 | 0.413 | 0.562 | 0.190 | 4.854 | 1.419 | 1.175 | 0.363 | 1.671 | 0.471 | 2.769 | 0.798 | 0.000 | 0.010 | 0.204 | 0.000 | 0.019 | 0.342 | ||
| Proteobacteria | ||||||||||||||||||||||||
| Alcaligenaceae | Sutterella | 0.236 | 0.089 | 0.020 | 0.017 | 0.527 | 0.074 | 0.547 | 0.056 | 0.957 | 0.359 | 0.066 | 0.020 | 0.465 | 0.184 | 0.222 | 0.080 | 0.306 | 0.000 | 0.001 | 0.402 | 0.000 | 0.003 | |
| Desulfovibrionaceae | Desulfovibrio | 0.129 | 0.041 | 0.043 | 0.025 | 0.263 | 0.055 | 0.110 | 0.029 | 0.533 | 0.159 | 0.279 | 0.107 | 0.248 | 0.108 | 0.212 | 0.121 | 0.004 | 0.141 | 0.167 | 0.008 | 0.190 | 0.320 | |
| Campylobacteriaceae | Campylobacter | 0.637 | 0.587 | 0.007 | 0.005 | 0.015 | 0.007 | 0.013 | 0.005 | 0.021 | 0.011 | 0.004 | 0.002 | 0.010 | 0.006 | 0.003 | 0.002 | 0.686 | 0.576 | 0.868 | 0.730 | 0.613 | 0.904 | |
| Succinivibrionaceae | Anaerobiospirillum | 0.752 | 0.470 | 0.017 | 0.005 | 0.178 | 0.051 | 0.099 | 0.037 | 0.835 | 0.259 | 0.298 | 0.131 | 0.531 | 0.206 | 0.075 | 0.020 | 0.686 | 0.002 | 0.868 | 0.730 | 0.005 | 0.904 | |
| Succinivibrio | 2.147 | 1.127 | 1.545 | 0.991 | 8.204 | 1.911 | 2.035 | 0.335 | 0.732 | 0.253 | 0.025 | 0.007 | 1.857 | 0.683 | 0.953 | 0.465 | 0.000 | 0.000 | 0.011 | 0.000 | 0.000 | 0.033 | ||
| Enterobacteriaceae | Escherichia/Shigella | 0.555 | 0.476 | 0.140 | 0.090 | 0.032 | 0.025 | 0.123 | 0.059 | 0.670 | 0.271 | 1.651 | 1.153 | 0.026 | 0.015 | 0.180 | 0.131 | 0.541 | 0.459 | 0.638 | 0.629 | 0.499 | 0.708 | |
| Spirochaetes | ||||||||||||||||||||||||
| Spirochaetaceae | Treponema | 0.000 | 0.000 | 0.000 | 0.000 | 0.570 | 0.273 | 0.030 | 0.015 | 0.000 | 0.000 | 0.000 | 0.000 | 0.061 | 0.035 | 0.020 | 0.013 | 0.018 | 0.000 | 0.000 | 0.029 | 0.000 | 0.000 | |
| UNCLASSIFIED | ||||||||||||||||||||||||
| Uncl. Bacteria | 0.096 | 0.032 | 0.044 | 0.006 | 0.084 | 0.023 | 0.036 | 0.009 | 0.132 | 0.020 | 0.116 | 0.027 | 0.136 | 0.046 | 0.102 | 0.028 | 0.009 | 0.219 | 1.000 | 0.015 | 0.274 | 1.000 | ||
Results are presented as mean and associated standard error of the mean (SEM). Uncl. unclassified; FDR, false discovery rate.