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. 2018 Jun 18;14:1627–1633. doi: 10.2147/NDT.S155521

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© 2018 He et al. This work is published and licensed by Dove Medical Press Limited

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Pedigree of the family. Filled symbols, affected subjects; open symbols, unaffected; a diagonal line through a symbol, deceased; short arrow, proband; half filled symbols, mutation carrier; circles, female; squares, male. DNA available in IV2, IV3, IV4, V5, V6, V7, and V8. The proband was IV2 (arrow), a 51-year-old female with the MAPT P301L mutation presenting as bvFTD clinically. One sibling (IV4) and two children of the patient (V6 and V8) were healthy mutation carriers with the same mutation.

Abbreviation: bvFTD, behavioral variant frontotemporal dementia.