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. 2018 Jun 25;8:9601. doi: 10.1038/s41598-018-28023-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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HMGB2 was abundant and partially co-expressed with PDGFRA in the intra-muscular spaces of SSP muscles from rat RCT models. (a) Representative images of immunostaining for HMGB2 in SSP muscles from rat RCT models (original magnification, x400). (b) Average total cell number and ratio of HMGB2-positive cells in the muscle and ectopic fat cells 2 and 16 weeks after tendon transection. n = 6 for each time point, 0.237 mm²/view. wks, weeks after tendon transection. n = 6 for each time point. *p < 0.05. **p < 0.001. (c) Representative images showing co-expression of HMGB2 and PDGFRA (arrowheads) in serial immunostained sections (original magnification, x400).