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. 2018 Jun 25;8:9602. doi: 10.1038/s41598-018-27977-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Expression levels of candidate genes selected based on co-expression with cx43. Means and standard deviations of RQ in three biological replicates are shown for the elongated (L) and short (S) regions of the caudal, dorsal and anal fin in original (stage 0) and regenerating tissue. See Fig. 1A for fin region codes; numbers 0 to 2 identify regeneration stages. Circles above bars indicate significantly elevated expression (P < 0.05 in paired t-tests) in comparisons between L and S tissue samples (i.e., compared to the bar matching the shade of the circle); note that the analysis was restricted to comparisons within the same fin type and the same regeneration stage. Genes highlighted in yellow and blue were identified in the first and second step of our gene selection procedure, respectively.