Fig. 5.

Comparison between HIV latency activation and cytokine induction. The amount of TNF-alpha (left panel) or MIP-1 alpha (right panel) produced in primary PBMC cultures (from Fig. 4) is plotted against the percentage of cells activated with the same concentration of compound in the J-Lat 10.6 latency assay. GFP+ cells in the J-Lat assay represent those cells that have been activated from latency during a 24 h incubation. Relevant statistical comparisons using a 2-sided t-test are described in the main text. Error bars represent ± 1 Standard Error.