Fig. 3.

iNOS expression and NO production is correlated with loss of coupled respiration. DCs were stimulated for 18 h by activators at the indicated doses (μg/mL). a Geometric MFI of iNOS, b nitrite (NO₂⁻) production, c coupled respiration, and d SRC were measured as described in Methods and in Fig. 1. Data shown are from one experiment representative of three experiments (mean and s.d. of duplicates (a, b) and s.e.m. of four to six replicates (c, d)). Data were analyzed using a one-way ANOVA. ***p < 0.001, **p < 0.01