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. 2017 Dec 26;103(4):1349–1358. doi: 10.1210/jc.2017-01698

Table 2.

Weighted Distributions of Thyroid Hormone and Raw Ultrasound Measurements by Study Visit of Sample Collection

n Selected Percentiles
25th 50th 75th 90th 95th Max
Visit 1 (median 10 wk)
Thyroid hormonesa
 TSH, µIU/mL 317 0.54 0.91 1.50 1.97 2.36 7.23
 FT4, ng/dL 374 1.16 1.39 1.64 2.07 2.57 12.5
 T4, µg/dL 364 8.70 10.0 11.3 12.6 13.7 18.0
 T3, ng/mL 304 1.11 1.31 1.61 1.86 2.11 2.91
Visit 2 (median 18 wk)
Ultrasound measurements
 HC, mm 389 141 148 159 166 173 202
 AC, mm 389 119 127 137 148 154 177
 FL, mm 390 25 27 29 31 32 40
 EFW, g 324 221 253 290 334 361 528
Thyroid hormonesa
 TSH, µIU/mL 317 0.98 1.36 1.91 2.52 3.15 6.08
 FT4, ng/dL 368 0.92 1.13 1.30 1.54 1.77 8.96
 T4, µg/dL 357 9.50 10.6 11.8 12.7 13.6 16.4
 T3, ng/mL 301 1.36 1.60 1.90 2.16 2.28 2.86
Visit 3 (median 26 wk)
Ultrasound measurements
 HC, mm 201 231 248 263 280 288 307
 AC, mm 201 207 221 239 255 263 280
 FL, mm 201 46 50 54 57 60 68
 EFW, g 201 810 978 1200 1442 1619 2032
Thyroid hormonesa
 TSH, µIU/mL 306 0.90 1.29 1.70 2.31 2.86 8.73
 FT4, ng/dL 349 0.81 1.00 1.18 1.44 1.97 12.5
 T4, µg/dL 333 9.20 10.3 11.4 12.7 13.5 21.7
 T3, ng/mL 286 1.36 1.62 1.90 2.15 2.37 2.79
Visit 4 (median 35 wk)
Ultrasound measurements
 HC, mm 221 308 317 326 333 340 366
 AC, mm 223 302 317 333 349 361 393
 FL, mm 223 65 68 71 74 75 77
 EFW, g 223 2323 2671 3034 3478 3643 4384
Thyroid hormonesa
 TSH, µIU/mL 270 0.97 1.35 1.92 2.44 2.71 6.22
 FT4, ng/dL 344 0.77 0.96 1.17 1.43 1.58 6.19
 T4, µg/dL 337 8.90 10.0 11.4 12.7 13.6 20.2
 T3, ng/mL 239 1.40 1.66 2.00 2.21 2.4 3.22
Birth (median 38 wk)
Birth weight, g 439 2946 3345 3660 3909 4139 4720

Analyses weighted by preterm birth case-control sampling probabilities.

a

Number of samples per hormone varied due to limitations in sample volume.