Fig. 4.

Relationship between average phylogenetic distance of genomes and protein sequence divergence for housekeeping proteins (left) and for ammonia-oxidation related proteins (right) for comammox Nitrospira, β-AOB and γ-AOB genomes. Boxplot are colored according to the groups to which the compared genomes belong. The y-axis shows the pairwise protein dissimilarity (fraction of differing amino-acid sites) for a set of 18 housekeeping proteins or 27 ammonia-oxidation related proteins, while the x-axis shows the corresponding pairwise dissimilarity for a set of 14 ribosomal proteins. Asterisks(* and **) indicates non-significant (P > 0.01) and significant (P < 0.01) difference between means of sequence dissimilarities of two studied groups, respectively