Table 3.
Uptake of bilateral mastectomy by variant status separately for women with a strong and no/minimal family history
| Variant status | Number of women who had BM within 12 months since enrolment (N = 128)a | Number of women who had not had a BM within 12 months but reported intention to undergo BM (N = 66)b,c | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Family history | No family history | Total | Family history | No family history | Total | |||||||
| Tot. N | N (%) | Tot. N | N (%) | Tot. N | N (%) | Tot. N | N (%) | Tot. N | N (%) | Tot. N | N (%) | |
| Variant carriers | 9 | 7 (77.8) | 9 | 9 (100.0) | 18 | 16 (88.9) | 1 | 1 (100.0) | 0 | 0 (0) | 1 | 1 (100.0) |
| No variant found | 65 | 16 (24.6) | 45 | 12 (26.7) | 110 | 28 (25.5) | 39 | 9 (23.1) | 26 | 0 (0) | 65 | 9 (13.8) |
| Total | 74 | 23 (31.1) | 54 | 21 (38.9) | 128 | 44 (34.4) | 40 | 10 (25.0) | 26 | 0 (0.0) | 66 | 10 (15.2) |
Variant carrier is the carrier of a BRCA1 or BRCA2 pathogenic variant
Tot. N Total N separately for women with a strong family history and no/minimal family history. BM bilateral mastectomy
a Self-reported as at 12-months post-enrolment questionnaire and as per medical records for women with missing self-report data
b Self-reported as at 12-months post-enrolment questionnaire
c Data on intention to undergo BM are missing for 18 women