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. 2017 Dec 18;114(3):431–442. doi: 10.1093/cvr/cvx245

Figure 7.

Figure 7

  Mitoprotection attenuated cardiomyocyte apoptosis and oxidative stress. (A) Representative myocardial Oil-red-O, dihydroethidium, and Ox-LDL staining, and quantification of intra-cardiac fat deposition, production of superoxide anion, and Ox-LDL immunoreactivity (n = 6/group). (B) The number of terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL, green) and caspase-3 (red) apoptotic cells was higher in MetS compared to Lean, but normalized in MetS + ELAM (n = 6/group). Red: connexin-43. (C) Myocardial expression of caspase-3 increased in MetS compared to lean, but normalized in ELAM-treated pigs (n = 6/group). *P < 0.05 vs. lean, †P < 0.05 vs. MetS + ELAM.