Skip to main content
. 2017 Oct 13;114(3):401–408. doi: 10.1093/cvr/cvx204

Figure 3.

Figure 3

Cardio-Nox4KO mice display higher interstitial fibrosis and lower capillary density after 6 weeks abdominal aortic banding (AAB). (A) Representative LV sections from Cardio-Nox4KO mice and WT littermates stained for myocardial fibrosis and capillaries; scale bars 50 μm. Mean data are shown on the right (n = 8–12/group). (B) Nox2 protein levels in Cardio-Nox4KO and WT mice (n = 4/group). (C–E) Protein levels of VEGF-A, HIF1α, p-eNOS, and total eNOS in LV of Cardio-Nox4KO mice compared to respective WT. Representative immunoblots are shown at the top and mean data below (n = 4/group). *P < 0.05, **P < 0.01 vs. respective sham controls. #P < 0.05, ##P < 0.01 vs. WT/AAB, two-way ANOVA with Tukey’s Multiple Comparison Test. All data are presented as mean ± SEM.

HHS Vulnerability Disclosure