Table 1.
Summary of mucin samples: the mucin names ending in S were obtained from the surface of the stomach mucosa and the ones ending in G from the glands.
| Leb | Sialic acid | MUC5AC | MUC6 | Health | η [cP] | |
|---|---|---|---|---|---|---|
| HM1NS | − | − | + + | + | Normal | 1.83 ± 0.15 |
| HM2NS | + + + | − | + + + | + | Normal | 1.95 ± 0.30 |
| HM3NG | − | − | + + | + + + | Normal | 2.27 ± 0.56 |
| HM4NG | + + + | − | + | + | Some Inflammation | 2.06 ± 0.31 |
| HM5T | + + | + + | + | + + | Tumor | 1.26 ± 0.12 |
| HM6N | + | − | + + | + | Normal | ND |
| PGM† | 9.0 ± 2.0 |
HM6N is from antrum and contains material from both glands and surface. Samples were selected based on being negative for the α1, 4 GlcNAc structure that has been demonstrated to have antibiotic activity60, to avoid this complicating factor, and therefore the gland and surface samples do not come from the same patient; “+” indicates the level of presence and “−” indicates the absence of particular structure. Data for positive control human mucin (HM6N) are included. Viscosity of mucin solutions at 15 mg/ml, η, given as average ± standard deviation (see text). †The viscosity of 15 mg/ml PGM solution reported here is from Martinez et al.43. ND indicates not determined.