Table 5.
Changes in LV longitudinal IVS and LW strain and SR, and LV circumferential IVS and FW strain and SR from baseline to 36 weeks.
| Parameter | Baseline | Follow-up | Change | P value |
|---|---|---|---|---|
| IVS pLS (%) | –14.4 (–10.8 – –16.6) | –16.6 (–12.5 – –19.8) | –1.0 (–5.9 – 0.5) | 0.027 |
| IVS pLSRs (1/s) | –0.67 (–0.88 – –0.6) | –0.74 (–0.95 – –0.63) | –0.08 (–0.2 – –0.06) | 0.181 |
| IVS pLSRe (1/s) | 0.89 (0.35–1.33) | 1.31 (0.92–1.82) | 0.21 (–0.12 – 1.04) | 0.02 |
| IVS pLSRa (1/s) (n = 17) | 0.61 (0.25–0.9) | 0.29 (0.2–0.53) | –0.05 (–0.48 – 0.13) | 0.495 |
| LW pLS (%) | –22.6 (–27.7 – –16.7) | –24.4 (–31.3 – –21.5) | –3.1 (–9.0 – 0.56) | 0.089 |
| LW pLSRa (1/s) (n = 18) | –1.08 (–1.36 – –0.94) | –1.19 (–1.56 – –0.98) | –0.07 (–0.51 – 0.11) | 0.17 |
| LW pLSRe (1/s) | 0.94 (0.51–1.97) | 1.85 (1.45–3.32) | 0.73 (–0.59 – 1.63) | 0.02 |
| LW pLSRa (1/s) | 0.89 (0.45–1.6) | 0.42 (0.26–0.68) | –0.22 (–1.43 – 0.11) | 0.03 |
| IVS pCS (%) | –18.8 (–22.5 – –16.3) | –20.7 (–23.9 – –17.7) | –1.07 (–4.53 – 1.02) | 0.2 |
| IVS pCSRs (1/s) | –0.97 (–1.24 – –0.82) | –0.95 (–1.28 – –0.8) | 0.02 (–0.15 – 0.2) | 0.7 |
| IVS pCSRe (1/s) (n = 20) | 0.98 (0.52–1.39) | 1.22 (0.88–1.54) | 0.06 (–0.17 – 0.45) | 0.02 |
| IVS pCSRa (1/s) (n = 19) | 0.56 (0.37–0.93) | 0.47 (0.35–0.66) | –0.12 (–0.42 – 0.05) | 0.106 |
| FW pCS (%) | –18 (–21.1 – –16) | –20.2 (–23.7 – –17.8) | –1.15 (–3.95 – 1.76) | 0.164 |
| FW pCSRs (1/s) | –0.95 (–1.18 – –0.79) | –0.95 (–1.29 – –0.82) | –0.02 (–0.29 – 0.18) | 0.511 |
| FW pCSRe (1/s) (n = 20) | 1.0 (0.75–1.29) | 1.17 (0.81–1.7) | 0.01 (–0.16 – 0.49) | 0.436 |
| FW pCSRa (1/s) (n = 19) | 0.51 (0.38–0.9) | 0.57 (0.39–0.63) | –0.01 (–0.18 – 0.08) | 0.76 |
Data expressed as median and IQR.
LV, left ventricular; SR, strain rate; IVS, interventricular septum; LW, lateral wall; FW, free wall; pLS, peak longitudinal strain; pLSRs, peak longitudinal systolic strain rate; pLSRe, peak longitudinal early diastolic strain rate; pLSRa, peak longitudinal atrial-diastolic strain rate; pCS, peak circumferential strain; pCSRs, peak circumferential systolic strain rate; pCSRe, peak circumferential atrial-diastolic strain rate.