Table 5.
Temporal trends in 5-year mortality risk, Nested-case control study
| 5-year cumulative hazard ratio (95% CI)a | ||||
|---|---|---|---|---|
| Epoch 1 (1977–1983) | Epoch 2 (1986–1991) | Epoch 3 (1992–1998) | Epoch 4 (2004–2008) | |
| Dementia cases during an epoch | ||||
| Deaths/N | 47/93 | 45/89 | 55/99 | 52/75 |
| Mortality Risk | Ref | 0.82 (0.55–1.21) | 0.70 (0.47–1.03) | 0.88 (0.57–1.34) |
| Matched Controls | ||||
| Deaths/N | 39/97 | 34/91 | 45/101 | 31/76 |
| Mortality Risk | Ref | 0.75 (0.44–1.27) | 1.07 (0.64–1.78) | 1.69 (1.00–2.84) |
Note: aComputed from Cox models with the earliest epoch as reference category. Controls were matched to dementia cases on age (at the date of dementia diagnosis), epoch, cohort (Original vs. Offspring), and sex.