Table 2. Accelerated EAE is not induced by CD4 T cells harvested from MHCII-deficient hosts.
Recipient Genotype | Donor CD4 T cells | Incidence of EAE | Mean Day of onset (± SEM) |
---|---|---|---|
WT | in vivo incubated* | 8/9 | 6.2 ± 0.6 |
CD19-BMHCIIxIgHMOG | in vivo incubated | 9/13 | 16.7 ± 2.3 |
* ≥ 3 weeks