Table 2.

Changes in fitness, neurocognitive and HRQoL outcomes by intervention and control group from baseline to 24-week follow-up

		Intervention Group					Control Group
			Baseline to 24 week follow up					Baseline to 24 week follow up			Comparison of Change – Intervention vs. Control
Fitness Outcomes	N	Baseline Value (SD)	Mean Change	T-statistica	p	N	Baseline Value (SD)	Mean Change	T-statistica	p	p
Hand grip, kg	50	19.95 (6.00)	1.13	2.65	0.01	24	22.27 (7.21)	1.14	1.27	0.22	0.99
Sit ups, number in 30 sec	49	15.08 (5.71)	2.49	3.27	0.002	22	15.70 (5.91)	2.5	2.13	0.05	0.99
Pushups, number in 30 sec	48	11.08 (5.83)	2.67	3.58	0.0008	21	11.61 (6.46)	2.14	1.52	0.14	0.72
Neurocognitive Outcomes
WASI Full Scale IQ Z-Score b	51	−0.18 (0.80)	0.13	2.07	0.04	24	−0.28 (0.51)	0.05	0.44	0.67	0.55
D-KEFS Inhibition Z-Score c	50	−0.04 (0.84)	0.23	2.82	0.007	22	−0.10 (0.70)	0.12	0.81	0.43	0.50
Quality of Life Outcomesd
PEDS QL4 Total Mean	52	74.19 (16.02)	3.83	2.63	0.01	24	75.32 (17.98)	1.71	0.70	0.49	0.44
PEDS QL4 Psychosocial Summary Mean	52	73.83 (16.40)	2.83	1.82	0.07	24	75.20 (16.99)	1.18	0.64	0.53	0.53
PEDS QL4 Physical Functioning Mean	52	74.88 (19.21)	5.65	2.69	0.01	24	75.54 (23.41)	2.70	0.58	0.57	0.57
PEDS QL4 Emotional Functioning Mean	52	75.72 (15.23)	2.64	1.85	0.07	24	78.80 (19.00)	−0.63	−0.22	0.83	0.25
PEDS QL4 Social Functioning Mean	52	76.54 (21.09)	3.87	1.92	0.06	24	76.80 (21.64)	4.58	1.40	0.18	0.85
PEDS QL4 School Functioning Mean	52	69.23 (20.85)	1.92	0.86	0.39	24	70.00 (21.21)	−0.42	−0.14	0.89	0.55

SD: standard deviation, HRQoL: health related quality of life

^apaired T-test

^bWechsler Abbreviated Scale of Intelligence, full scale IQ score converted to a z-score (higher score indicates better function)

^cDelis-Kaplan Executive Function system, Color-Word Interference Test (higher score indicates better function)

^dPediatric Quality of Life Inventory (PedsQL) v4.0 (higher score indicates better quality of life)