Table 4.
Comparison of Clinical Correlates and Clinical Outcome Variables by coronary artery abnormality (CAA) status at 9–15 months in patients with Kawasaki Disease (KD) and CAAs at diagnosis
| Variable | Statistics/ Category | Resolution of CAAs at 9–15 months (N = 9) | Persistence of CAAs at 9–15 months (N = 15) | P- value |
|---|---|---|---|---|
| Age at diagnosis, years | Mean (SD) | 6.46 (4.65) | 5.73 (5.40) | 0.61 |
| Age range at diagnosis | <1 year (%) | 1 (11) | 4 (27) | 0.86 |
| 1–5 years (%) | 3 (33) | 5 (33) | ||
| >5 years (%) | 5 (56) | 6 (40) | ||
| Sex | Male (%) | 6 (67) | 11 (73) | 0.99 |
| Female (%) | 3 (33) | 4 (27) | ||
| Race | White (%) | 7 (78) | 10 (67) | 0.47 |
| Black (%) | 1 (11) | 0 (0) | ||
| Asian (%) | 0 (0) | 0 (0) | ||
| Hispanic (%) | 1 (11) | 4 (27) | ||
| Other (%) | 0 (0) | 1 (7) | ||
| Classic KD | Yes (%) | 2 (29) | 10 (71) | 0.16 |
| No (%) | 5 (71) | 4 (29) | ||
| Unknown | 2 | 1 | ||
| Illness duration before diagnosis, days | Mean (SD) | 8.78 (4.29) | 13.71 (7.80) | 0.12 |
| Defervescence duration before diagnosis, days | Mean (SD) | 0.33 (1.00) | 2.07 (4.86) | 0.34 |
| CRP at diagnosis, g/dL | Mean (SD) | 15.23 (11.09) | 12.83 (7.68) | 0.60 |
| Platelet count at diagnosis, x 109/L | Mean (SD) | 438.4 (229.1) | 602 (374.7) | 0.38 |
| IVIg #1 given | Yes (%) | 9 (100) | 14 (93) | 0.99 |
| No (%) | 0 (0) | 1 (7) | ||
| HDA duration, days | Mean (SD) | 5.44 (5.64) | 10.47 (9.14) | 0.13 |
| IVIg Resistance | Yes (%) | 1 (11) | 11 (79) | 0.003 |
| No (%) | 8 (89) | 3 (21) | ||
| Unknown | 0 | 1 | ||
| Fever duration after diagnosis, days | Mean (SD) | 0.67 (1.00) | 6.07 (7.10) | 0.03 |
| CRP at 4–8 weeks, g/dL | Mean (SD) | 0.41 (0.32) | 0.66 (0.74) | 0.75 |
| CRP at 9–15 months, g/dL | Mean (SD) | 0.50 (0.00) | 0.33 (0.09) | 0.07 |
| Platelet count at 4–8 weeks, x 109/L | Mean (SD) | 332.3 (135.1) | 393.3 (127.2) | 0.43 |
| Platelet count at 9–15 months, x 109/L | Mean (SD) | 261.3 (80.56) | 280.1 (118.8) | 0.87 |
CAA = Coronary Artery Abnormality, CRP = C-Reactive Protein, HDA = High-Dose Aspirin, IVIg = Intravenous Immunoglobulin, KD = Kawasaki Disease, SD = Standard Deviation.