Table 1.

Demographic and clinical features of 190 FD-ET vs. 68 Co

	FD-ET n = 190	Co n = 68	Significance
Current age in years	56.7 ± 9.7	56.4 ± 9.6	0.79a
Female gender	128 (67.4)	23 (33.8)	<0.001b
Education in years	16.6 ± 2.9 [16.0]	16.7 ± 3.6 [17.0]	0.84c
White race	183 (96.3)	65 (95.6)	0.73d
English language	186 (97.9)	65 (95.6)	0.38d
Current cigarette smoker	4 (2.1)	0 (0.0)	0.58d
Number of prescription medications	1.9 ± 2.0 [1.0]	2.5 ± 2.8 [2.0]	0.50c
Number of medications that could predispose to balance issues or falls	0.6 ± 1.0 [0.0]	0.7 ± 1.0 [0.0]	0.67c
CIRS score	4.2 ± 3.3 [4.0]	4.0 ± 3.8 [3.0]	0.50c
Musculoskeletal disease			0.41b
None	136 (71.6)	55 (80.9)
Mild problem	36 (18.9)	10 (14.7)
Moderate problem	16 (8.4)	3 (4.4)
Severe problem	2 (1.1)	0 (0.0)
BDI	4.5 ± 4.5 [3.0]	4.5 ± 4.6 [3.0]	0.83c
Genetic load1	1.4 ± 0.9 [1.0]	0.0 ± 0.0 [1.0]	<0.001c
Total tremor score	6.7 ± 2.2 [6.5]	5.85 ± 2.3 [5.5]	0.006c
Number of falls in past year	0.3 ± 0.7 [0.0]	0.2 ± 0.6 [0.0]	0.24c
Number of near-falls in past year	2.8 ± 10.8 [1.0]	2.4 ± 12.5 [0.0]	0.015c
ABC-6 total score	494.1 ± 128.3 [540.0]	530.7 ± 74.0 [550.0]	0.03c
Tandem gait (number of steps to the side)	0.9 ± 1.7 [0.0]	0.5 ± 1.2 [0.0]	0.10c
Tandem stance (number of seconds without falling to the side)	9.0 ± 2.6 [10.0]	9.6 ± 1.9 [10.0]	0.048c

Values are mean ± standard deviation [median] or number (percent).

^aStudent’s t test.

^bChi-square test.

^cMann-Whitney test.

^dFisher’s exact test.

ABC (Activities of Balance Confidence), BDI (Beck Depression Inventory), CIRS (Cumulative Illness Rating Scale).

¹The number of reportedly affected first-degree relatives was defined as the genetic load.