Table 3.
Multivariable Models Relating Sex to Presence of Plaque and Presence of Positively Remodeled Plaque Among ART-Treated HIV-Infected Women and Men (n = 142)
Presence of Any Plaque | Presence of Positively Remodeled Plaque | |||
---|---|---|---|---|
Odds Ratio [95% CI] | P-value | Odds Ratio [95% CI] | P-value | |
Age, y | 6.6 [3.0, 16.0] | < 0.0001 | 3.4 [1.7, 7.2] | 0.0007 |
Male sex | 3.8 [1.4, 11.4] | 0.01 | 3.7 [1.4, 10.9] | 0.01 |
White race | 5.2 [0.8, 49.7] | 0.11 | 2.8 [0.5, 24.4] | 0.29 |
Black/African American race | 5.2 [0.8, 48.0] | 0.10 | 2.2 [0.4, 18.4] | 0.41 |
Hispanic race/ethnicity | 0.7 [0.07, 9.0] | 0.81 | 0.5 [0.04, 5.6] | 0.54 |
Current hypertension | 1.6 [0.6, 5.0] | 0.38 | 1.4 [0.6, 3.8] | 0.45 |
Current diabetes mellitus | 0.8 [0.2, 2.9] | 0.71 | 0.7 [0.2, 2.5] | 0.63 |
HDL-C, mg/dL | 0.9 [0.7, 1.1] | 0.28 | 1.0 [0.8, 1.3] | 0.97 |
VAT, cm2 | 1.0 [0.9, 1.0] | 0.30 | 1.0 [0.9, 1.0] | 0.18 |
NRTI use | 1.2 [0.1, 9.9] | 0.88 | 1.4 [0.2, 12.5] | 0.77 |
NNRTI use | 1.1 [0.4, 3.6] | 0.82 | 1.0 [0.3, 3.1] | 0.99 |
PI use | 0.6 [0.2, 1.8] | 0.36 | 0.8 [0.3, 2.2] | 0.64 |
Odds ratios and P-values were determined by multivariable logistic regression. Odds ratios for continuous variables are reported per a 10-unit change in the variable of interest. Odds ratios for categorical variables compare odds of presence versus absence of parameter.
HDL-C, high-density lipoprotein cholesterol; NNRTIs, non-nucleoside reverse transcriptase inhibitors; NRTIs, nucleoside reverse transcriptase inhibitors; PIs, protease inhibitors; VAT, visceral adipose tissue.