RV1B infection induces LIGHT expression. A, LIGHT mRNA expression in lungs of mice infected a single time with RV1B after 14 h compared to naïve animals, normalized to L32. B, LIGHT mRNA expression in RV1B-infected alveolar epithelial cells (A549). Fold increase normalized to GAPDH. C, LIGHT mRNA expression in sorted lung cell populations from 6 to 8 naïve and RV1B-infected mice. Fold increase normalized to L32. D, LIGHT mRNA expression in lungs of mice treated with control IgG or anti-Ly6G and infected with RV1B for 14 h, normalized to L32. Results are means ± SEM from 3-4 mice/group or replicates of 2 cell cultures, and representative of at least 2 experiments each. *P < .05