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. Author manuscript; available in PMC: 2018 Jun 26.
Published in final edited form as: J Am Coll Cardiol. 2016 May 3;67(17):2032–2046. doi: 10.1016/j.jacc.2016.02.049

TABLE 2.

CMR Analysis of Ventricular Structure and Function*

Saline AAV1.SERCA2a p Value†
Baseline (n = 9) Final (n = 5) Baseline (n = 10) Final (n = 8) Baseline Group/Time Interaction
rRV EDV, ml/m2 108 (99–129) 161 (110–165) 111 (104–138) 132 (124–156) 0.710 0.878
RV ESV, ml/m2   45 (40–57)   82 (54–91)   48 (41–55)   51 (45–66) 0.971 0.101
RVEF, %   58 (56–64)   50 (44–51)   59 (58–63)   61 (56–63) 0.754 0.008
RV mass, g/m2   56 (49–69)   62 (57–63)   64 (55–71)   59 (55–62) 0.489 0.014
Stroke volume, ml/m2   58 (55–64)   55 (37–64)   69 (52–71)   71 (57–81) 0.200 0.084
LV EDV, ml/m2   87 (78–93)   89 (66–108)   97 (92–105) 109 (105–112) 0.090 0.022
LV ESV, ml/m2   31 (29–33)   33 (28–42)   38 (35–40)   38 (33–43) 0.157 0.571
LVEF, %   64 (63–67)   61 (61–62)   62 (58–63)   65 (63–66) 0.620 0.085

Values are median (IQR).

*

Baseline was at 2 months after model creation and final was at 4 months after model creation (and 2 months after gene transfer).

†

Independent samples Student t test.

CMR = cardiac magnetic resonance imaging; RV = right ventricular; EDV = end-diastolic volume; EF = ejection fraction; ESV = end-systolic volume; LV = left ventricular; other abbreviations as in Table 1.