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. 2018 Jun 26;11:366. doi: 10.1186/s13071-018-2924-3

Table 2.

Mean live Ixodes holocyclus counts and efficacy of fluralaner applied once topically to catsa

Day of infestation
Day -1 14 28 42 56 70 84
Untreated control
 Arithmetic mean 7.3 6.2 6.4 6.2 5.5 6.8 5.9
 Geometric mean 7.0 5.8 5.6 5.8 4.6 6.5 5.7
Fluralaner spot-on
 Arithmetic mean 0.0 0.0 0.0 0.0 0.0 0.0 0.0
 Efficacy (%) 100.0 100.0 100.0 100.0 100.0 100.0 100.0
 Geometric mean 0.0 0.0 0.0 0.0 0.0 0.0 0.0
 Efficacy (%) 100.0 100.0 100.0 100.0 100.0 100.0 100.0
Comparison t(18.0) = 23.2, P < 0.0001 t(18.0) = 15.8, P < 0.0001 t(18.0) = 10.7, P < 0.0001 t(18.0) = 17.7, P < 0.0001 t(18.0) = 8.9, P < 0.0001 t(18.0) = 22.4, P < 0.0001 t(18.0) = 21.1, P < 0.0001

aEfficacy was based on an assessment of tick viability at 48 h post-treatment and at 72 h post challenge infestations