Table 3.
Differentially expressed TAG species identified between adipose tissues from IS, IR and T2DM individuals
| ID | TAG | MW | Fatty acid composition | Fatty acids identities | Comparison | Fold change | FDR p value |
|---|---|---|---|---|---|---|---|
| TAG16A | C46:4 | 770.7 | C18:2, C18:2, C10:0 | Linoleic acid, linoleic acid, capric acid | IS vs T2DM | − 0.62 | 0.005 |
| IR vs T2DM | − 0.53 | 0.01 | |||||
| TAG21 | C48:5 | 796.7 | C18:2, C18:3, C12:0 | Linoleic acid, linolenic acid, lauric acid | IR vs T2DM | − 0.39 | 0.0005 |
| IS vs T2DM | − 0.38 | 0.0013 | |||||
| TAG22 | C48:4 | 798.7 | C18:2, C18:2, C12:0 | Linoleic acid, linoleic acid, lauric acid | IR vs T2DM | − 0.96 | 0.002 |
| TAG2A | C38:1 | 664.7 | C18:1, C16:0, C4:0 | Oleic acid, palmitic acid, butyric acid | IS vs T2DM | − 1.00 | 0.0007 |
| TAG32 | C50:3 | 828.8 | C16:1, C16:1, C18:1 | Palmitoleic acid, palmitoleic acid, oleic acid | IR vs T2DM | − 0.78 | 1.37E–05 |
| IS vs T2DM | − 0.76 | 5.62E–05 | |||||
| TAG61 | C56:7 | 904.8 | C20:4, C18:1, C18:2 | Arachidonic acid, oleic acid, linoleic acid | IS vs T2DM | 0.81 | 0.0006 |
| IR vs T2DM | 0.74 | 0.001 | |||||
| TAG64 | C56:4 | 910.8 | C18:1, C18:2, C20:1 | Oleic acid, linoleic acid, gadoleic acid | IS and IR vs T2DM | 0.98 | 0.004 |
| TAG65 | C56:3 | 912.8 | C20:1, C18:1, C18:1 | Gadoleic acid, oleic acid, oleic acid | IR vs T2DM | 0.51 | 0.002 |
| IS vs T2DM | 0.54 | 0.002 | |||||
| TAG7 | C40:2 | 690.7 | C6:0, C16:0, C18:2 | Caproic acid, palmitic acid, linoleic acid | IS vs T2DM | − 1.07 | 1.26E–05 |
| IR vs T2DM | − 0.83 | 0.0002 | |||||
| TAG74 | C58:7 | 934.8 | C18:6, C24:0, C16:1 | C18:6, lignoceric acid, palmitoleic acid | IS and IR vs T2DM | 0.48 | 0.007 |
| TAG75 | C58:4 | 938.7 | C18:3, C24:0, C16:1 | Linolenic acid, lignoceric acid, palmitic acid | IR vs T2DM | 0.69 | 0.0005 |
| IS vs T2DM | 0.73 | 0.0005 | |||||
| TAG9 | C42:2 | 718.7 | C18:2, C12:0, C12:0 | Linoleic acid, lauric acid, lauric acid | IS vs T2DM | − 0.77 | 0.0008 |
| IR vs T2DM | − 0.71 | 0.001 |
MW molecular weight, fatty acid composition, fatty acid identity, fold change between specified groups are also indicated