Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mean false discovery proportion (FDP) versus the correlation due to sample overlap over 100 simulation runs and a covariate-modulated false discovery rate (cmfdr) cut-off of 0.05. Here d=100,000 SNPs were simulated, of which 400 were non-null in both study 1 and study 2, i.e., have positive pleiotropic effects. The test statistics for study 2 were used as a covariate for study 1
