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. 2018 Jun 25;19:494. doi: 10.1186/s12864-018-4859-7

Table 4.

Psychiatric Genetics Consortium data, with varying amounts of overlapping controls

#Overlapping Correlation #Discoveries, raw #Discoveries, adjusted
0 0 255.3 (239.8,270.8) 256.5 (239.7,273.3)
2000 0.09 322.3 (310.1,334.5) 206.5 (190.1, 222.9)
4000 0.18 479 (437.4,520.6) 194.5 (172.8, 216.2)
6000 0.27 827.6 (762.1, 893.1) 186.4 (162.9, 209.9
8000 0.36 1442.7 (1325.2, 1560.2) 188.9 (156.8, 221.0)
10000 0.45 2985.7 (2785.6, 3185.8) 212.7 (181.3, 244.1)

The test statistics for bipolar disorder were used as a covariate for schizophrenia in the covariate-modulated fdr (cmfdr). SNPs having a cmfdr < 0.05 were called as discoveries. Data is presented as mean (95% confidence interval)