Table 4.
#Overlapping | Correlation | #Discoveries, raw | #Discoveries, adjusted |
---|---|---|---|
0 | 0 | 255.3 (239.8,270.8) | 256.5 (239.7,273.3) |
2000 | 0.09 | 322.3 (310.1,334.5) | 206.5 (190.1, 222.9) |
4000 | 0.18 | 479 (437.4,520.6) | 194.5 (172.8, 216.2) |
6000 | 0.27 | 827.6 (762.1, 893.1) | 186.4 (162.9, 209.9 |
8000 | 0.36 | 1442.7 (1325.2, 1560.2) | 188.9 (156.8, 221.0) |
10000 | 0.45 | 2985.7 (2785.6, 3185.8) | 212.7 (181.3, 244.1) |
The test statistics for bipolar disorder were used as a covariate for schizophrenia in the covariate-modulated fdr (cmfdr). SNPs having a cmfdr < 0.05 were called as discoveries. Data is presented as mean (95% confidence interval)