Table 2.

Test results found to have the greatest area under the curve in ROC analysis

Measure	Clinical test
Test Rank	1	2	3
Screening for 2–3 sign CI
Test	MT phoria (Δ)	NPC break (cm)	NPC recovery (cm)
AUC (p-value)	0.795 (< 0.001)	0.766 (< 0.001)	0.744 (< 0.001)
Cutpoint	≥ 3 exo	≥ 6.0	≥ 8.5
Sensitivity	0.625	0.804	0.750
Specificity	0.858	0.690	0.664
Screening for 3 sign CI
Test	PFV / Phoria	PFV blur (Δ)	NPC break (cm)
AUC (p-value)	0.938 (< 0.001)	0.863 (< 0.001)	0.853 (< 0.001)
Cutpoint	≤ 1.90	< 14	≥ 6.0
Sensitivity	0.889	0.778	1.000
Specificity	0.908	0.837	0.633
Screening for symptomatic 2–3 sign CI
Test	CISS	NPC break (cm)	NPC recovery (cm)
AUC (p-value)	0.823 (< 0.001)	0.781 (< 0.001]	0.777 (< 0.001)
Cutpoint	≥ 16	≥ 7.5	≥ 9.0
Sensitivity	1.000	0.679	0.750
Specificity	0.638	0.783	0.669
Screening for symptomatic 3 sign CI
Test	AA (D)	PFV / Phoria	NPC break (cm)
AUC (p-value)	0.937 (< 0.001)	0.925 (< 0.001)	0.916 (< 0.001)
Cutpoint	≤ 10.0	≤ 1.9	≥ 9.5
Sensitivity	1.000	0.833	0.833
Specificity	0.800	0.886	0.859
Screening for symptomatic 2–3 sign CI with accommodative dysfunction
Test	NPC break (cm)	NPC recovery (cm)	CISS
AUC (p-value)	0.915 (< 0.001)	0.895 (< 0.001)	0.850 (< 0.001)
Cutpoint	≥ 7.5	≥ 10.0	≥ 16
Sensitivity	0.941	0.941	1.000
Specificity	0.780	0.731	0.614

AUC = Area under ROC curve; MT = Modified Thorington; NPC = Near Point of Convergence; PFV = Positive Fusional Vergence; AA = Accommodative amplitude; CISS = Convergence Insufficiency Symptom Survey score