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Changes in histone deacetylase (HDAC) activity in the cerebral cortex at 4 hours (A) and 24 hours (B) after traumatic brain injury (TBI) in adult mice. The HDAC inhibitor sodium butyrate significantly attenuated the HDAC activity in the cortex. The data were normalized to samples with trichostatin A and presented as the mean ± SEM. *p< 0.05 vs control or TBI without sodium butyrate. #p< 0.05 vs control without sodium butyrate.
