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. Author manuscript; available in PMC: 2018 Jun 27.
Published in final edited form as: Oncogene. 2009 Nov 16;29(7):1041–1049. doi: 10.1038/onc.2009.396

Figure 4.

Figure 4

Xrn2 enhances proliferation and inhibits expression of the squamous differentiation marker involucrin in Beas2b cells. (a) Immunoblot for HA-tagged Xrn2 expression in Beas-2B cells. (b) MTT assay for proliferation of Beas-2B cells cultured under nondifferentiating conditions (SF) or differentiating conditions (FCS). (c) Quantitative real-time PCR to detect involucrin transcript accumulation in Beas-2B cells overexpressing Xrn2 cultured under nondifferentiating conditions with serum-free media (SF) or differentiating conditions with FCS. (d) Micrographs of Beas-2B cells cultured under differentiating conditions (FCS). Insets depict magnifications of representative areas of the micrographs to show differences in morphology.