Table 1.
SNPs associated with spontaneous incidence of lung tumor in inbred mice
| dbSNPa | Chr | Pos (bp) | Allelesb | MAF | Mean SI (%)c
|
P-values | |
|---|---|---|---|---|---|---|---|
| Mi/Mi | Ma/Ma | ||||||
| rs27328255 | 2 | 147 067 787 | T/C | 0.500 | 33.6 | 1.8 | 6.68E – 07 |
| rs13476822 | 2 | 147 204 386 | G/A | 0.478 | 32.9 | 1.8 | 1.94E – 06 |
| rs33240516 | 2 | 146 756 804 | T/C | 0.455 | 34.6 | 1.8 | 3.16E – 06 |
| rs27294933 | 2 | 146 900 320 | G/A | 0.455 | 33.1 | 1.8 | 4.79E – 06 |
Abbreviations: LD, linkage disequilibrium; MAF, minor allele of frequency; SNPs, single-nucleotide polymorphisms.
SNPs with P-value <P = 5.43 × 10−6 (that is, genome-wide threshold P = 0.10) were presented; for those SNPs that are in complete LD, only one of them was presented.
Alleles in bold are minor allele of SNPs.
SI indicates spontaneous incidence of lung tumor (%); Mi is a minor allele and Ma is a major allele.