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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Shock. 2018 Dec;50(6):671–676. doi: 10.1097/SHK.0000000000001089

Figure 1. Thrombin provokes immediate PAI-1 release from platelets.

Figure 1

Platelets underwent near complete (>95%) degranulation of PAI-1 in response to thrombin stimulation as shown with released versus remaining. Control platelets did not degranulate over the duration of the experiment with a significant amount of PAI-1 remaining in the cells at the end of the experiment. n=4. *p<0.013 when compared to control lysate (same time point). #p<0.007 compared to thrombin supernatant.