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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Arthritis Rheumatol. 2018 May 20;70(7):1133–1143. doi: 10.1002/art.40469

Figure 1. CD4+ TEM and TEMRA cells are not expanded in patients with active untreated IgG4-RD.

Figure 1

Contour plots showing different frequencies of CD4+CD45RO+CD27lowCD62Llow TEM cells (A) and CD4+CD45RA+CD27lowCD62Llow TEMRA cells (C) in the peripheral blood of two representative healthy controls (HC 1 and HC 5) and two representative patients with IgG4-RD (#1 and #13) before and after glucocorticoid treatment. Box plots of CD4+CD45RO+CD27lowCD62Llow TEM cells (B) and CD4+CD45RA+CD27lowCD62Llow TEMRA cells (D) in the peripheral blood of healthy controls and patients with IgG4-RD displaying mean values and range before and after glucocorticoid treatment. P values are based on the Mann-Whitney test.