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. 2018 Jun 25;16:40. doi: 10.1186/s12969-018-0257-6

Table 3.

Treatment targets and treatment strategy

Statements Consensus
Treatment targets 100%
The overall goal is clinical inactive disease within 1 year after initiation of therapy, ideally under a glucocorticoid-free treatment regimen. Under some circumstances, low-dose glucocorticoids or intermittent intravenous methylprednisolone pulse therapy may be acceptable.
The following interim improvementa is targeted:
• At least a moderate improvement within 6 weeks after initiation or substantial change in therapy.
• At least a major improvement within 3 months after initiation or substantial change in therapy.
General treatment strategy 92%
The consensus treatment strategies for JDM serve to harmonize existing therapies in clinical practice.
The treatment strategy generally consists of a treat-to-target strategy, i.e. therapies are modified according to reaching or failing previously established targets. In addition, there is a more intensive first (induction) treatment phase (6–8 weeks) and a less intensive subsequent (maintenance) phase.
Components of the initial therapy include glucocorticoids and glucocorticoid-sparing DMARDs.

a American College of Rheumatology/European League Against Rheumatism criteria (categories: no, minimal, moderate, major improvement) [34]